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Index > Protein center > Clcn5(Gene name) > Rat
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  • Clcn5 (Gene name),
  • H(+)/Cl(-) exchange transporter 5 (Protein name ),  CLCN5_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Clcn5;
    Protein name:
    H(+)/Cl(-) exchange transporter 5;
    Alternative:
    Chloride transporter ClC-5;Chloride channel protein 5(ClC-5);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with NEDD4 and NEDD4L.
    Function:
    Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosome lumen. May play an important role in renal tubular function.
    Subcellular Location:
    Golgi apparatus membrane Multi-pass membrane protein Endosome membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    746
    Sequence:
    50:
    MDFLEEPIPG | VGTYDDFNTI | DWVREKSRDR | DRHREITNKS | KESTWALIHS | 
    100:
    VSDAFSGWLL | MLLIGLLSGS | LAGLIDISAH | WMTDLKEGIC | TGGFWFNHEH | 
    150:
    CCWNSEHVTF | EDRDKCPEWN | SWSQLIISTD | QGAFAYIVNY | FMYVLWALLF | 
    200:
    AFLAVSLVKA | FAPYACGSGI | PEIKTILSGF | IIRGYLGKWT | LVIKTITLVL | 
    250:
    AVSSGLSLGK | EGPLVHVACC | CGNILCHCFN | KYRKNEAKRR | EVLSAAAAAG | 
    300:
    VSVAFGAPIG | GVLFSLEEVS | YYFPLKTLWR | SFFAALVAAF | TLRSINPFGN | 
    350:
    SRLVLFYVEF | HTPWHLFELV | PFIVLGIFGG | LWGALFIRTN | IAWCRKRKTT | 
    400:
    QLGKYPVVEV | LIVTAITAIL | AFPNEYTRMS | TSELISELFN | DCGLLDSSKL | 
    450:
    CDYENHFNTS | KGGELPDRPA | GVGVYSAMWQ | LALTLILKIV | ITIFTFGMKI | 
    500:
    PSGLFIPSMA | VGAIAGRLLG | VGMEQLAYYH | HDWGIFNSWC | SQGADCITPG | 
    550:
    LYAMVGAAAC | LGGVTRMTVS | LVVIMFELTG | GLEYIVPLMA | AAMTSKWVAD | 
    600:
    ALGREGIYDA | HIRLNGYPFL | EAKEEFAHKT | LAMDVMKPRR | NDPLLTVLTQ | 
    650:
    DSMTVEDVET | IISETTYSGF | PVVVSRESQR | LVGFVLRRDL | IISIENARKK | 
    700:
    QDGVVSTSII | YFTEHSPPMP | PYTPPTLKLR | NILDLSPFTV | TDLTPMEIVV | 
    746:
    DIFRKLGLRQ | CLVTHNGRLL | GIITKKDVLK | HIAQMANQDP | ESILFN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    SMR:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat H(+)/Cl(-) exchange transporter 5
    MSDS:
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    ELISA Kit for Rat H(+)/Cl(-) exchange transporter 5
    Cat.:
    E12784m
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    Packing:
    96T
    ELISA Kit for Rat H(+)/Cl(-) exchange transporter 5
    Cat.:
    E12784r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat H(+)/Cl(-) exchange transporter 5
    Cat.:
    E12784h
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat H(+)/Cl(-) exchange transporter 5
    Cat.:
    E12784p
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat H(+)/Cl(-) exchange transporter 5
    Cat.:
    U12784h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat H(+)/Cl(-) exchange transporter 5
    Cat.:
    U12784p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat H(+)/Cl(-) exchange transporter 5
    MSDS:
    Please sign in first.
    CLIA Kit for Rat H(+)/Cl(-) exchange transporter 5
    Cat.:
    U12784m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat H(+)/Cl(-) exchange transporter 5
    Cat.:
    U12784r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat H(+)/Cl(-) exchange transporter 5
    Cat.:
    P12784Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat H(+)/Cl(-) exchange transporter 5
    Cat.:
    P12784Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat H(+)/Cl(-) exchange transporter 5
    Cat.:
    P12784Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat H(+)/Cl(-) exchange transporter 5
    Polyclonal Antibody for Rat H(+)/Cl(-) exchange transporter 5
    Monoclonal Antibody for Rat H(+)/Cl(-) exchange transporter 5
    Monoclonal Antibody for Rat H(+)/Cl(-) exchange transporter 5
    Monoclonal Antibody for Rat H(+)/Cl(-) exchange transporter 5
    Monoclonal Antibody for Rat H(+)/Cl(-) exchange transporter 5
    Monoclonal Antibody for Rat H(+)/Cl(-) exchange transporter 5
    Protein for Rat H(+)/Cl(-) exchange transporter 5
    Protein for Rat H(+)/Cl(-) exchange transporter 5
    Protein for Rat H(+)/Cl(-) exchange transporter 5
    Protein for Rat H(+)/Cl(-) exchange transporter 5
    Protein for Rat H(+)/Cl(-) exchange transporter 5

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and functional expression of rat CLC-5, a chloride channel related to kidney disease."
      Steinmeyer K. , Schwappach B. , Bens M. , Vandewalle A. , Jentsch T.J.
      J. Biol. Chem.270:31172-31177(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      "Identification of a new outwardly rectifying Cl- channel that belongs to a subfamily of the ClC Cl- channels."
      Sakamoto H. , Kawasaki M. , Uchida S. , Sasaki S. , Marumo F.
      J. Biol. Chem.271:10210-10216(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Kidney.
    3. 3.
      "Residues important for nitrate/proton coupling in plant and mammalian CLC transporters."
      Bergsdorf E.-Y. , Zdebik A.A. , Jentsch T.J.
      J. Biol. Chem.284:11184-11193(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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